Dr.Kamal Singh Rathore

Mucoadhesion in drug delivery system has recently gained interest among pharmaceutical scientists as a means of promoting dosage form residence time as well as improving intimacy of contact with various absorptive membranes of the biological system. Besides acting as platforms for sustained release dosage forms bioadhesive polymers can themselves exert some central control over the rate and amount of drug release.

Drug delivery system is changing at a rapid pace. Nanotechnology means that what we are working with is very small. It generally means that we are working on the molecular level or, at least, in sizes of a few nanometers in the semiconductor industry Smaller…smaller….smaller mantra translates to Faster….. Faster…faster. .

As safety, quality and purity are important prerequisites for a drug, United States Food and Drug Administration (USFDA) provided the validation and process controls for ensuring the identity, strength, quality, purity and stability of drug. Process validation is defined as establishing documented evidence that a specific process will produce a product meeting its predetermined specifications and quality attributes.

Vaccine is a biological preparation which is used to establish or improve immunity to a particular disease. But edible vaccines are thegenetically modified plants offer the exciting prospect of mass-producing antibodies and vaccines for medical use by inserting human or viral genes into crop plants.

Biosimilars or Follow-on biologics are terms used to describe officially-approved subsequent versions of innovator biopharmaceutical products made by a different sponsor following patents and exclusivity expiry on the innovator product. Biosimilars are not generic; they differ from generic drugs because their active ingredients are huge molecules with intricate structures.

Colon specific diseases are often inefficiently managed by oral therapy, Because most orally administered drugs are absorbed before arriving in the colon. Therefore, colon-specific drug delivery systems, which can deliver drugs to the lower Gastrointestinal tract without releasing them in the upper GI-tract, can be expected to Increase the quality of life for patients suffering from colon specific diseases.

QbD is design decisions based on through formulation and process understanding as these relate to the intended use. Quality by design means designing and developing a product and associated manufacturing processes that will be used during product development to ensure that the product consistently attains a predefined quality at the end of the manufacturing process.

"Reengineering is the fundamental rethinking and radical redesign of business processes to achieve dramatic improvements in critical, contemporary measures of performance such as cost, quality, service and speed." The key words in the preceding definition are the italicized ones.

Benchmarking is the continuous process of identifying, understanding and adapting practices from other organizations to improve the performance of your own organization. The process involves continuously assessing the quality of goods and services against standards of best practiceJapanese industrialists devised benchmarking in 1950s' to identify and copy "the best practices".

Head hair is the most noticeable part of human body. So most of hair care products and treatments are for head hair. Various ailments like Alopecia, Dandruff, Folliculitis, Decoloration etc. pose threat to hair and hair growth. Remedies to such hair diseases include- Allopathic, Ayurvedic and Homeopathic treatments along with hair transplantation to cope baldness.