Megh - Articles

Molecular Mechanism of Drug resistance

Drug resistance is the reduction in effectiveness of a drug in curing a disease or improving a patient's symptoms.We frequently refer to bacteria as being resistant to antibiotics, but rarely do we consider what that means. Even the most resistant bacterium can be inhibited or killed by a sufficiently high concentration of antibiotic; patients, however, would not be able to tolerate the high concentration required in some cases. Read

By: Megh | 19/12/2009 | Science

Molecular Mechanism of Drug resistance

• Antibiotic resistance should be defined in terms of clinical outcomes, not laboratory methods • Resistance occurs by means of four main mechanisms more than one may be present in a single bacterium • Resistance mechanisms have probably evolved from genes present in organisms producing antibiotics • Resistance genes occur not only in bacteria that carry disease but also in commensal bacteria, to which we are continuously exposed and which are found in food, the environment, and animals Read

By: Megh | 11/10/2009 | Science