Recent Activity
Collectively Cleft Lip and Cleft Palate has a major clinical impact requiring surgical, dental, orthodontic, speech, hearing and psychological treatments or therapies throughout childhood
The genetic basis of cleft lip with or without cleft palate remains unresolved
Population-based candidate-gene studies can be an effective strategy for identifying genes involved in the etiology of disorders
Preterm cleft children with low birth weight should be screened for the presence of other birth defects
Maternal cigarette smoking during pregnancy as a risk factor for having a child with cleft lip/palate has been suggested by several epidemiologic studies
There have been several investigations assessing the prevalence of associated malformations in geographically defined populations
Some techniques eliminate the severe cleft nasal deformity seen in many secondary cases
The high frequency of associated anomalies has obvious implications for the genetic counseling offered to all patients at cleft palate and craniofacial centers
It is suggested that maternal smoking is one of many factors of importance in the etiology of cleft lip and cleft palate in humans
Possible risks of Cleft Lip and Cleft Palate should be considered when prescribing certain medications for women in their reproductive years

