Clenbuterol main action
Short but very exact and detailed about steroid like medication Clenbuterol. Clenbuterol is a medication, a selective ?2 adrenostimulant. Activating ?2 adrenergic receptors, it has a powerful bronchodilator effect. Pharmacological action of Clenbuterol. The selective ?2-adrenostimulant has a bronchodilator and secretolytic action. It activates ?2-adrenergic receptors, stimulates adenylate cyclase, increases the concentration of cAMP in cells, which, affecting the protein system, prevents myosin ability to connect to actin and promotes bronchi relaxation. It hinders the release of mast cell mediators that provoce a bronchospasm and bronchi inflammation. It reduces swelling and congestion in the bronchi, improves mucociliary clearance. In large doses it causes tachycardia, fingers tremor. The bronchodilator effect begins after the inhalation in 10 minutes, maximum - in 2-3 hours, duration of action - 12 hours. Pharmacokinetics of Clenbuterol. Absorption is high. Therapeutically effective concentrations are formed in the plasma in 15 min after a single intake and persist for 7-24 hours. It is brought off by the kidneys. T1 / 2 - 3 hours. Indications for Clenbuterol. COPD, bronchial obstruction, bronchial asthma.
It hinders the release of mast cell mediators that provoce a bronchospasm and bronchi inflammation. It reduces swelling and congestion in the bronchi, improves mucociliary clearance. In large doses it causes tachycardia, fingers tremor. The bronchodilator effect begins after the inhalation in 10 minutes, maximum - in 2-3 hours, duration of action - 12 hours. Pharmacokinetics of Clenbuterol. Absorption is high. Therapeutically effective concentrations are formed in the plasma in 15 min after a single intake and persist for 7-24 hours. It is brought off by the kidneys. T1 / 2 - 3 hours. Indications for Clenbuterol. COPD, bronchial obstruction, bronchial asthma.
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