Mesothelioma Research And Bridging The Gap
Continued research regarding mesothelioma and the link to asbestos exposure is necessary if we ever hope to find a cure. Imagine someone you love returning home from the second world war. They find a job as an auto mechanic, raise a family, and play by the rules. Decades later, they tragically die from mesothelioma cancer because someone failed to warn them of the dangers of asbestos fibers. Does any reasonable person believe this is fair or just? Of course not. Unfortunately, we cannot go back in time and prevent the asbestos exposure. But what we can do is try to promote public awareness about this deadly disease and highlight some of the great research being done.
One interesting study is called, "Malignant mesothelioma: attributable risk of asbestos exposure." By R Spirtas, E F Heineman, L Bernstein, G W Beebe, R J Keehn, A Stark, B L Harlow, and J Benichou - Occup Environ Med 1994;51:804-811 doi:10.1136/oem.51.12.804. Here is an excerpt:
"OBJECTIVES--To evaluate a case-control study of malignant mesothelioma through patterns of exposure to asbestos based upon information from telephone interviews with next of kin. METHODS--Potential cases, identified from medical files and death certificates, included all people diagnosed with malignant mesothelioma and registered during 1975-1980 by the Los Angeles County Cancer Surveillance Program, the New York State Cancer Registry (excluding New York City), and 39 large Veterans Administration hospitals. Cases whose diagnosis was confirmed in a special pathology review as definite or probable mesothelioma (n = 208) were included in the analysis. Controls (n = 533) had died of other causes, excluding cancer, respiratory disease, suicide, or violence. Direct exposure to asbestos was determined from responses to three types of questions: specific queries as to any exposure to asbestos; occupational or non-vocational participation in any of nine specific activities thought to entail exposure to asbestos; and analysis of life-time work histories. Indirect exposures were assessed through residential histories and reported contact with family members exposed to asbestos. RESULTS--Among men with pleural mesothelioma the attributable risk (AR) for exposure to asbestos was 88% (95% confidence interval (95% CI) 76-95%). For men, the AR of peritoneal cancer was 58% (95% CI 20-89%). For women (both sites combined), the AR was 23% (95% CI 3-72%). The large differences in AR by sex are compatible with the explanations: a lower background incidence rate in women, lower exposure to asbestos, and greater misclassification among women. CONCLUSIONS--Most of the pleural and peritoneal mesotheliomas in the men studied were attributable to exposure to asbestos. The situation in women was less definitive."
Another good study is called, "Chrysotile asbestos is the main cause of pleural mesothelioma" by Allan H. Smith, MD, PhD, Catherine C. Wright, MPH
School of Public Health, University of California, Berkeley, CA. Here is an excerpt:
"Abstract - In contrast to amphibole forms of asbestos, chrysotile asbestos is often claimed to be only a minor cause of malignant pleural mesothelioma, a highly fatal cancer of the lining of the thoracic cavity. In this article we examine the evidence from animal and human studies that relates to this issue. Reported data do not support widely quoted views regarding the relative inertness of chrysotile fibers in mesothelioma causation. In fact, examination of all pertinent studies makes it clear that chrysotile asbestos is similar in potency to amphibole asbestos. Since asbestos is the major cause of mesothelioma, and chrysotile constitutes 95% of all asbestos use world wide, it can be concluded that chrysotile asbestos is the main cause of pleural mesothelioma in humans."
If you found either of these excerpts interesting, I would urge you to read the studies in their entirety. We all owe a debt of gratitude to these researchers, and should do our best to promote public awareness. This article should not be construed as legal or medical advice."
Questions and Answers
Pleural mesothelioma develops in the lining of the lung called the pleura or pleural membrane. Pleural Mesothelioma is one of the most common types of Mesothelioma.
Mesothelioma is an asbestos related cancer caused by exposure to asbestos over a long period of time.
Immunocytochemical staining with anti-TM should be added to the battery of tests to increase the diagnostic sensitivity and specificity for differentiating mesothelioma from pulmonary adenocarcinoma
Mesothelioma is a rare form of cancer almost exclusively caused by asbestos exposure. Pleural mesothelioma is the most common type of mesothelioma, a rare cancer that develops in the mesothelial cells that make up the mesothelium, a membrane that lines many of the body's organs and cavities.
Pleural mesothelioma is the most diagnosed form of mesothelioma and is over 60 percent of all cases of mesothelioma discovered in the United States yearly. Pleural mesothelioma is a cancer that affects the lining of the lungs and chest cavity, called the pleura.
Recently two antifolate-based combinations with apparently higher efficacy than older regimens have emerged: the pemetrexed/cisplatin regimen and the raltitrexed/oxaliplatin regimen
Cancer translational research brings together scientists' and clinicians' suggestions to develop solutions to biomedical complications. This kind of applied research strives to offer strategies to questions surrounding the etiology, pathology, diagnosis, prevention and treating cancer.
Orbs are actually a lumpectomy or quadrantectomy combined with rotating the breast tissue or mobilize the flap into the cavity of the surgery time fill is removed. It also includes the comparative change in shape and size is doing in relation to breast and moved if necessary, does not affect the conversion of the breast. The deferred plan the reconstruction is not part of endoplasmic techniques. Both procedures are performed by specific thoracic surgeons.
What every woman fears for is losing her self confidence , losing hope and losing her personality. The term "Breast Cancer" is a very negative word and that it creates negative vibrations in her heart. So, to make her comfortable with the basics of breast cancer and to make her means any woman understand that this type of cancer is the least dangerous than all cancers and that if it is detected early then you will fight with it successfully. Causes, Symptoms, treatment, discussed in detail.
Mesothelioma is a rare cancer that originates in the mesothelium. The mesothelium is the protective lining that covers the body's internal organs. Mesothelioma occurs when the mesothelium cells start to divide uncontrollably.
Chemotherapy is a treatment for killing cancerous cells which is given intravenous or extra-venous to the cancer patient. Even breast cancer patients have to go through the treatment. This treatment mainly focuses on the cancerous cells that are spread in the blood stream in the whole body . If any cancerous cells are there then they are killed by the chemotherapy medicine. The medicine is very costly and it has to be taken for one or two days continuously for every 21 days .
Collectively Cleft Lip and Cleft Palate has a major clinical impact requiring surgical, dental, orthodontic, speech, hearing and psychological treatments or therapies throughout childhood
The genetic basis of cleft lip with or without cleft palate remains unresolved
Population-based candidate-gene studies can be an effective strategy for identifying genes involved in the etiology of disorders
Preterm cleft children with low birth weight should be screened for the presence of other birth defects
Maternal cigarette smoking during pregnancy as a risk factor for having a child with cleft lip/palate has been suggested by several epidemiologic studies
Discuss this Article
