Propecia Approved for the Treatment of Hairloss

Posted: Sep 16, 2008 | Comments: 0 | Views: 10 | Bookmark and Share

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CLICK HERE TO ORDER PROPECIA and stop hair loss. Propecia, the only medically approved oral prescription hair loss medication. Prescription Propecia has been shown in numerous clinical studies to be the most effective hair loss treatment yet available for stopping potential hair loss while promoting hair re-growth.

What is Propecia?

Propecia® (Finasteride), available in the UK since 1997, is the first and only oral medication approved by both the M.C.A. and the F.D.A. for the treatment of male pattern hair loss. Effective in around 99% of male patients at preventing further hair loss as well generating new growth on both the vertex and the anterior mid-scalp areas.

The longest controlled clinical trial of a hair loss treatment ever reported showed that men who took Propecia® (finasteride 1 mg) compared to men who took a placebo had a considerable difference in their hair counts after five years, according to data presented at the 59th Annual Meeting of the American Academy of Dermatology.

The new study showed a difference of 277 hairs in a one-inch diameter circle of scalp in favor of men treated with Propecia for five years (n=219) vs. those who received a placebo (n=15). Baseline hair counts of all men at the start of the study averaged 876 hairs in the one-inch diameter circle.

“This study provides new, long-term scientific data that Propecia helped the majority of men with male pattern baldness keep the amount of hair they have,” said Keith Kaufman, M.D., senior director, Clinical Research, Merck Research Laboratories. “The study was also the first controlled clinical trial to evaluate the course of untreated hair loss over a five-year period and to show the progressive nature of male pattern hair loss.”

APPROVED WORLDWIDE FOR THE TREATMENT OF HAIR LOSS

Made by Merck & Co., Inc., Propecia is indicated for the treatment of certain types of hair loss in men only, based upon studies. Propecia is a once-a-day treatment and is the only pill for male pattern hair loss approved for use world wide. The five-year data are from investigational extension studies of double- blind placebo-controlled clinical trials that first demonstrated the safety and efficacy of Propecia in 1,553 men age 18 to 41 with mild-to-moderate male pattern baldness (androgentic alopecia) in the vertex region (top of the head). Efficacy in bi-temporal recession (hair loss at the temples) has not been established.

Men who entered the initial year long studies of Propecia were randomized to receive either Propecia (n=779) or placebo (n=774). The initial year long studies were extended on an annual basis, with only a small number of men remaining on placebo in subsequent years, as specified in the study design. Men who completed each one-year extension were given the opportunity to enroll in the next one-year extension, for up to five years. The five-year data presented focused on the results of men who continued on the same therapy—either Propecia or placebo—for the entire five years.

Five-year Propecia efficacy results

The studies assessed the efficacy of Propecia by four separate endpoints: hair counts in a one-inch diameter circle of the scalp; assessments of “before” and “after” photographs by a panel of dermatologists; patient questionnaires and investigator assessments of changes in scalp hair growth. The effectiveness of Propecia vs. placebo was demonstrated as follows:

• Hair count: At the start of the studies, baseline hair counts averaged 876 hairs in a one-inch diameter area of scalp. By the end of the first year, men taking Propecia had an average of 126 more hairs than men taking the placebo. This difference continued to grow, and, by the end of the fifth year, the net difference between the groups increased to 277 hairs in favor of the men taking Propecia. At the end of the fifth year, 65 percent of men taking Propecia (n=219) maintained or improved their hair count compared to their hair count at the start of the studies, while all of the men on placebo (n=15) lost hair count.

Men treated with Propecia were more likely to say that: their bald spot was getting smaller and the appearance of their hair had improved, also that they had experienced increased hair growth.

Important information about Propecia for use as a treatment for hair Loss

Propecia is not to be used by women or children. Furthermore, women must not use Propecia when they are, or may potentially be, pregnant as it may cause abnormalities of the male baby’s sex organs. In addition, women should not handle crushed or broken tablets when they are pregnant or may potentially be pregnant.

Propecia tablets are coated, which will prevent contact with the active ingredient during normal handling provided that the tablets have not been broken or crushed.

If the treatment does not show results within 12 months, further treatment is unlikely to be of benefit. If treatment is stopped, the hair that is gained will gradually be lost.

Propecia hair loss treatment is currently available worldwide.

(ArticlesBase SC #564164)

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