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American Society of Aesthetic Lipodissolve Responds to American Society of Aesthetic Plastic Surgery
Author: Khalid Mahmud, M.D.,FACP  | Posted: 21-06-2007 | Views: 25 | Rating: (54)  (?) 
The American Society of Aesthetic Lipodissolve [ASAL] objects to the inclusion of “Lipodissolve” in the recent warning against injection therapy (MESOTHERAPY) for localized fat reduction issued by the American Society of Aesthetic Plastic Surgery [ASAPS]. The procedure, Lipodissolve was introduced by the founders of ASAL in 2001 as distinct from “Mesotherapy”. The ASAL took care to include ingredients which were safe and whose mechanism of action was understood. The ASAL diligently limited training only to physicians and their nurses to perform the procedure. The ASAL and its original cohort, “Network Lypolysis”, thus trained more than 300 physician in Europe, and so far, more than 200 physicians in the United States.
ASAPS is incorrect in stating that there are no data relative to the effectiveness and safety of the procedure. As it relates to Lipodissolve, more than 50,000 treatment sessions have been reported in European and American peer reviewed journals demonstrating: a] objective evidence of improvement, based on actual measurements and pictures, in approximately 90% of the patients, and b] a paucity of serious side effects.1-4,6,7 Serious side effects reported with liposuction such as death, fluid overload, epinephrine and lidocaine toxicity, thrombosis, fat embolism and complications of general anesthesia have not been reported with Lipodissolve therapy.5
The main ingredient in the Lipodissolve formula is phosphatidylcholine [PC], a lipid. It is dissolved in a bile salt [deoxycholate], which is how it exists in bile where it helps to breakdown the ingested fat cells and digest fat on a daily basis. When injected in to the unwanted superficial body fat, it similarly breaks down fat cells and “digests fat”, as it does naturally in proximal duodenum. In the subcutaneous area the dead fat cells are then gradually removed by the body’s physiologic repair mechanisms, the same way as after any trauma or even after liposuction which leaves dead fat cells in the area to be removed by similar physiologic processes. PC along with other phospholipids are significant dietary source of essential fatty acids. Mammalian cell membranes are primarily composed of PC and other phospholipids mixed with cholesterol esters and salts to maintain fluidity. In other words it is not some foreign or toxic substance.
ASAPS’s statement that this “procedure is not FDA approved” is misleading. FDA approves drugs and devices, not procedures. ASAL maintains that there is no FDA approval requirement relative to phosphatidylcholine for two reasons. One, it is a “supplement” and as such has been used for years for liver health, cholesterol and other possible benefits. Supplements do not require FDA approval and can be administered by injection,(as are vitamins and minerals as in Meyer’s cocktail, intravenous nutrition or hyper-alimentation consisting of amino acids, vitamins, minerals, lipids, and others. Second, in Lipodissolve, the ingredients are mixed by a compounding pharmacist upon a physician’s order for specific patients, which does not require FDA approval [FDA Modernization Act Section 503a Compounding Pharmacy].
Lipodissolve is not a surgical procedure. Accordingly, ASAL has compiled an advisory board that includes highly credentialed physicians with diverse but relevant backgrounds in the fields of dermatology, aesthetic surgery and internal medicine. These individuals are experienced clinicians, speakers, writers, researchers and teachers, and provide advice regarding the procedure and its evolution. They conduct training workshops for other physicians in the U.S. So far the North American advisers have performed more than 2,000 Lipodissolve procedures with satisfactory results in more than 90% of the patients – without any serious side effects. The ASAL has an on going monitoring process to record these events.
References:
1. Hasengschwandtner,F. Phosphatidylcholine treatment to induce lypolysis. Journal of Cosmetic Dermatology, 2005; 4:308-313
2. Duncan, ID, Hasengschwandtner,F. Lipodissolve for Subcutaneous Fat Reduction and Skin Retraction. Aesthetic Surgery Journal, 2005-September/October; 25(5):530-43
3. Heinrich, K-G. Efficacy of Injections of Phosphatidylcholine into Fat Deposits, A non-surgical alternative to liposuction in body contouring. Presented as a scientific publication at the convention “Operative Dermatology” at Frankfurt, October 28-31, 2004
4. Palmer, M, Curran, J, Bowler, P. Clinical experience and safety using phosphatidylcholine injections for the localized reduction of subcutaneous fat: a multicentre, retrospective UK study. Journal of Cosmetic Dermatology, 2006; 5:218-25
5. Platt, MS, et.al. Deaths associated with liposuction: case reports and review of the
literature. Journal Forensic Science. 2002, Jan; 47(1):205-7
6. Duncan,DI,Chubaty,R,Clinical Safety Data and Standards of Practice for Injection Lipolysis: A Retrospective Aesthetic Surgery J, 2006;26:000.
7. Hasengschwandtner,F, Furtmueller,F, Spanbaner,M,Silye,R.Detailed Documentation of Lipolysis Treatment: Blood Values,Histology, and Ultrasound Findings.Aesthetic Surgery J 2007, 27:204-211
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Article Source: http://www.articlesbase.com/medicine-articles/american-society-of-aesthetic-lipodissolve-responds-to-american-society-of-aesthetic-plastic-surgery-168663.html
 About the Author:Khalid Mahmud, MD, FACP
• Founder, Innovative Directions in Health – the only Anti-Aging Clinic in Minnesota
• Board certified: Anti-Aging Medicine, Internal Medicine, Hematology and Oncology
• Former chief of Medicine and head of Oncology, North Memorial Medical Center, Minneapolis
• Frequent author, a national speaker.
• Author of the book, “Keeping aBreast: Ways to STOP Breast Cancer”.
• http://www.idinhealth.com
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Frequently Asked Questions
What is the stomach firm pad under the compression garment for
By: Kimberly | 12-09-2008
I had liposuction on tuesday, sep 9 2008. This is my 3 day after surger. Under my garment was a piece of firm foam pad that was over my abs, the nurse said it was okay to take this off, however; i am wondering if it needs to stay on under the compressiion garment. I had it on my stomach, flanks, love handles, inner & outer thighs, hips and knees?
I had a tummy tuck and lipo suction done. I am 10 ...
By: Birdie | 27-08-2008
I had a tummy tuck and lipo suction done. I am 10 weeks post. I feel like I was smaller 3 weeks ago. I feel like a am bigger now around my tummy area. Is this normal???
Returning fat on inner thighs!!
By: Ann | 24-08-2008
I am 5'3" and currently weigh 117. I am 51 years old. I had lipo last July (2007) on my inner and outer thighs and love handles. Recently, I've noticed fat returning on my inner thighs. I weigh EXACTLY what I weighed the day I came home for having the lipo. I walk miles daily and work with weights at the gym twice a week. How can this fat be returning? I am feeling so discouraged because I work so hard to look good. I don't want to go through the surgery again!! HELP...............why is the fat coming back!! Thanks, ANN
Will weight loss AFTER lipo target the non-lipo'd areas?? i.e. reverse of weight gain after lipo
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