Dietary Folic Acids : Why Do We Need Them More?
Macho-man – that’s what most of the kids next door aspire to be, especially when cable operators keep on pounding their little minds with Arnold movies! This reflects the natural animal tendency to grow strong and live healthy, & we are no exception as far as basic instincts are concerned! For a healthy body & a sound mind, proper cellular nutrition is a major determining factor & folic acid is one such component that plays a significant part in cell division & growth.
In a biological system, a meshwork of molecules is involved in various metabolic activities at cellular levels, churning out a potpourri of free radicals & oxidants. Now these free radicals & oxidants may cause mayhem within the cell as they can oxidize and damage many inherent molecules including DNA! Now, various reports have suggested that folic acid, which is commonly known as folate or better, as vitamin B9, acts as a “good-cop” protecting the cells with its “anti-oxidant gun”! It is also responsible for the synthesis of two of the four basic monomers the DNA is built up of i.e. adenine and thymine. So, besides its antioxidant activity, it also helps in proper DNA replication & transcription which is central to a biological cell, as a processor is to a computer!
The deficiency of folic acid may kick in a cascade of several disorders like, atherosclerosis, heart attack, stroke, Alzheimer's disease, cervical and colon cancer, osteoporosis, depression, dementia, cleft lip and palate, hearing loss, and of course, neural tube defects (NTD).
It has been observed that, if consumed daily, in required amount by women during early pregnancy, folic acids reduces the risk of any serious Neural tube defect (a birth defect involving incomplete development of the brain and spinal cord) to their babies by up to 70%! So, folic acid is an essential component for pregnant women & their babies as it helps the infant put up a fight against several neural disorders of brain and spinal cord like spina bifida, anencephaly and encephalocele.
Gradual positive changes can be observed if high amounts of folic acid are taken before or during the first few weeks of pregnancy. Folic acid is specifically important one month before conception and at least three months afterwards. If omitted at an early stage or if consumed later on, it fails to show its usefulness.
Though, folic acid even in very high levels is non-toxic, but still CDC i.e. Center for Disease Control and Prevention recommends that a woman, during pregnancy, should not take more than 1000µg of synthetic folic acid a day, in normal conditions. Though, it varies from 0.4 mg/day to 10 mg/day or more depending on the severity of the folic acid deficiency & the problem associated.
Folic acid needs vitamins B12 and B6 as catalysts to carry out its functions effectively. So, it won’t be of any use without appropriate presence of these vitamins. The RDA recommendation for vitamin B12 generally ranges from 0.5 to 1.0 mg/day and for vitamin-B6 from 10 to 250 mg/day.
Recent studies have reveled that folic acid also helps in the formation of normal red blood cells (RBC). This diverse array of functions certainly requires us to have sufficient quantities of folic acid in our diet!
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Vitamin B9, is also referred to as folic acid or folacin or folate; and its chemical name is pteroylglutamic acid. Folic acid is the parent compound of a large group of naturally occurring, structurally related compounds collectively known as the folates. In 1941, a substance was extracted from spinach leaves and named folic acid - from the Latin word "folium" for leaf, which was found to be useful in the cure for anaemia.
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Steroids, once notoriously famous for their abuse by bodybuilders, fitness buffs, and professional athletes, have found their way into wardrobes of many young damsels nowadays.
Steroids are well famous for their testosterone simulating properties of building muscle mass and enhancing endurance and thus have been notoriously abused to boost stamina and athletic performance since shortly after their conception. As a result, the incidences of non-medicinal use of steroids have increased considerably in recent years, particularly amongst adolescents & high school students often without their parents ever getting to know about it!
Search Engines, what a luxury they are! For they are a real comfort to those bootlegging myriad of extrajudicial poppin’ pills, which frequently include Steroids! These pills are often based on various male sex hormones that lead to the development of secondary male sexual characteristics, for instance, testosterone. They are medically termed as Androgens & Anabolic Steroids, although on the street, they are better known as - juices, toners or candy!
Steroids have no doubt, proved their medicinal worth over a period of time; however, they have also been notoriously abused for their muscle building attributes. Consequently, they have, since long, been put to an auxiliary use for increasing the muscular mass and physical strength, particularly by people involved in different sports and bodybuilding.
Steroids or anabolic steroids are a class of hormones affecting the development and growth of sex organs. The artificially synthesized hormones are frequently related to the hormone testosterone which is a potent androgenic hormone produced chiefly by the testes in males and & also to lesser extent by ovaries in females.
We all go through a range of dynamically regulated hormonal changes through different stages of our lives. These changes are characteristic to many variables such as age, sex, pathological condition, and exogenous administration of drugs or in the form of dietary steroids.
Testosterone is an anabolic steroid & a potent androgenic hormone which is produced naturally in the body by the male testes as well as female ovaries, although the proportional production in males and females vary significantly.
Testosterone, which is a type of anabolic-androgenic steroids, is known to build muscle tissue & cause the development of male secondary sex characteristics.
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