Aging Seen Without The Emperor's New Clothes
A. Aging, lifetime and age
Aging = to become old, show the effects or the characteristics of increasing age, the increasing liferime. The effects and characteristics of not only the totality of the system, but also of each and every component, and of components of the components of the system. The system is the totality of the components.
lifetime = the duration of the existence of a living being, an organism, or an inanimate thing, a material, star or subatomic particle.
age = the length of an existence extending from its beginning to any given time.
B. More and more research works related to old age are published in scientific periodicals
The lengthening list of work-accounts comprises a wide array of subjects apparently related to old age, including:
- A variety of constitutional impairments,
- a variety of impaired biological processes,
- a variety of impaired genetic materials and expressions,
- a great variety of suggested things to consume or do or avoid for alleviating the symptoms,
- and a great variety of anti-aging suggestions.
C. Some examples of statements:
- A little stress may keep cells youthful.
- Intestinal stem cells, that replenish the lining, go awry in elderly flies, similar to what happens in certain human stem cell populations.
- Yeast, worms and people may age by similar mechanisms.
- Nearly all organisms experience aging.
- In aging muscles and neurological problems, energy greedy organs, there are mitochondria
dysfunctions.
- Age-related growing 'leakiness' in cell nucleus membrane may contribute to aging and even to diseases such as Parkinson's and Alzheimer's.
- Age-Related Hearing Impairment, presbycusis, is a complex elderlies disease caused by
overexpression of glutamate due to interaction between environmental and genetic factors.
D. Right they are: "Nearly all organisms experience aging". But why "nearly"?
Why don't "scientists" accept the obvious fact that genes are organisms and "experience aging", too?
Not only yeast, worms and people. Also genes and the interdependent-genes-communes, genomes. Theye are both organisms. They are alive. It is their "lifehood" that makes us and all life forms "alive".
By plain common sense - my favorite scientific approach - they should also be "experiencing aging"...
E. The aging of genes contributes to organisms aging
Since a genome is a cooperative commune of interdependent genes, many of its member genes "modulate its aging" to various extents at various time-rates depending on circumstances and environment and on their individual composition and functioning history. Various things happen to them or affect them and impair their functionalities.
In my plain commonsensical mind "interaction between environmental and genetic factors" is a description of organism's "aging". And in my boy's-like view of the emperor's new clothes organism's aging comprises aging of its genes-genome, and genes and genomes age as we age, and we age also as a result of the aging of our genes and genomes...
F. Finally, re "Theories about human cellular aging supported by new research"
http://www.eurekalert.org/pub_releases/2008-12/asfc-bta111908.php
"Research presented at American Society for Cell Biology conference:
Aging yeast cells accumulate damage over time, but they do so by following a pattern laid down earlier in their life by diet as well as the genes that control metabolism and the dynamics of cell structures such as mitochondria, the power plants of cells."
Cellular Aging? What is Cellular Aging?
Complexly instrumented future spacestations accumulate damage over time, and their residents, too, age and accumulate damage over time. Yes, the functionality of the stations' residents and of their intruments and equipment is impaired with age. Wonder why?
The reason for the impairment with age of the highly active instrumented-equipped stations and of their resident crew is that they "follow a pattern laid down earlier in their life by diet as well as by the residents who control metabolism and the dynamics of the stations' structures such as mitochondria, their power plants."
G. Enough. Cells just house organisms. The resident genes-genomes are THE organisms.
About time that "scientists" refresh conceptions and comprehensions and attitudes and research plannings and peer-reviewings. Let their science evolve...
Dov Henis
(Comments From The 22nd Century)
http://blog.360.yahoo.com/blog-P81pQcU1dLBbHgtjQjxG_Q--?cq=1
EVOLUTION Beyond Darwin 200
http://www.physforum.com/index.php?showtopic=14988&st=405&#entry396201
http://www.the-scientist.com/community/posts/list/100/122.page#1407
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