To read about vitamine k and other information, visit the acide folique site.
Mostly one will find vitamin K coming in the group of lipophilic, hydrophobic vitamins which is needed for posttranslational modification in specific proteins as having the usage in blood coagulation. In general vitamin k belongs to the 2-methyl-1,4-naphthoquinone derivatives family. There are many other forms of vitamin k such as Vitamin K1 which is also known as phylloquinone or phytomenadione . Sometimes vitamin K2 know n as menatetrenone which is producecd from bacteria in the Larger Intestine of the human body. So by this one will not find dietary deficiency unless the intestines are disturbed heavily due to lesser production of normal flora. Now three synthetic forms of vitamin K like vitamins K3, K4, and K5 , are prevalent in many areas like pet food industry along with inhibiting fungal growth .
Most of the members of the vitamin K group is having methylated naphthoquinone ring structure like having varied aliphatic side chain joined at 3-position . Also phylloquinone is known as vitamin K1 carrying four isoprenoid residues in the side chain and in them one shows its unsaturation form. Vitamin K also plays an important role in the carboxylation of many glutamate residues present in proteins for the production of gamma-carboxyglutamate residues . Mostly vitamin k residues are located in the protein domains called as Gla domains. So this vitamin k's gla-residues helps in the biological activity of all the popular Gla-proteins in the body. So in this way vitamin k aids in the movement of three physiological processes like blood coagulation, bone metabolism, and osteocalcin , matrix gla protein , and Vascular biology and many more activities .
Most of the time consumers of vitamin k suffers from allergic reaction but there is no such cases fo toxicity having high doses of vitamin k . but another form of vitamin k called as vitamin k 3 has shown the signs of toxicity in many patients. And also the food and drug association banned the intake of vitamin k as its over dosage leads to allergic reactions, hemolytic anemia etc. And also it leads to the cytotoxicity in cells of liver and other organs . Common people dont shows the lack of vitamin k symptoms and also there is no such reports available showing its deficiencies in healthy people.
Most of the symptoms emerges known as secondary vitamin K Groups which might leading to secondary vitamin K deficiency like bulimics, stringent diets, and on anticoagulants. Many drugs related to vitamin K deficiency like salicylates, barbiturates, and cefamandole are available in the market. Consumption of vitamin k shows equal responses on both male and female sexes in normal life . There are negative side effects of vitamin k symptoms which occurs due to deficiencies of it like heavy menstrual bleeding, anemia, bruising, and bleeding of the gums and nose and many other symptoms.
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